Cause by the pathology change of kidney blood-vessel and kidney spherule, capillary loop (kidney spherule) have filter function. Although considered in endocrinology all sorts of 2 model the hair interpretation of the cause of diabetic sex nephrosis formulates theory, but the main factor that its develop and start are tall blood sugar. 2 model because carbohydrate metabolizes,diabetic sex nephrosis is disorder long-term compensation inadequacy is caused.
2 model the blood sugar of the diabetic is general on the high side. Blood sugar is elevatory damage kidney spherule. As the elapse of time, they disappeared, those who replace is to cannot keep clear of scar organization of blood. The kidney spherule that remain is less, nephritic job is poorer. Final, what they stopped to handle waste material is cleared, the body is toxic. In this phase, the patient needs to replace remedy, lest have a model dialytic or kidney transplant.
Blood is having main effect in the kinetic theory development in diabetic nephrosis, be in especially inside arterial high pressure and kidney in blood stream obstacle: The fundamental key that carries arterial alcohol is lopsided, make the blood pressure inside kidney spherule elevatory. Long-term hypertension causes the structural change of kidney spherule: It is tall percolation filtration above all, send sexual make water and protein to release formerly quickly, use form form next (kidney spherule is sclerotic) replace kidney spherule to organize, spherule of completely out-of-the-way kidney, reduce its to filter ability, admit chronic kidney failure.
Diabetic control is poorer, the risk with terminal kidney failure is higher, happen more quickly. The probability that the diabetic encounters complete kidney failure is not high. Before because be in,need kidney replaces remedy, the most person in them dies at the heart attack or apoplectic. Additional, diabetic amalgamative smoking or the patient that road of chronic make water affects, the risk of its kidney failure can increase.